Course Overview: The societal challenge of the 2019 Coronavirus Disease (COVID-19) pandemic increases the global needed for technology-facilitated learning. Additionally, there is a growing need for experts who can design and deliver technology-facilitated courses that enable course participants to successfully apply course knowledge content and contribute innovative solutions to societal challenges. The H3ABioNet Bioinformatics Instructional Design Online Course is the first course in a series of online Train-the-Trainer courses with an expected outcome of teams of trainers with diverse expertise to support the performance of bioinformatics tasks in the H3Africa community. The objective of the H3ABioNet Bioinformatics Train-the-Trainer project is to develop teams of bioinformatics trainers who are able to design and deliver effective, efficient and engaging learning experiences on bioinformatics topics to the H3Africa community with the best use of H3ABioNet and H3Africa resources. For additional information, please email