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DTSTAMP:20260716T075719Z
UID:ec9365af-8425-439a-9514-bd8bcaf03f44
DTSTART:20200511T090000Z
DTEND:20200515T180000Z
DESCRIPTION:Proteins and their interactions are the mainstays of any cellul
 ar process. Studying these interactions at atomic detail is invaluable\, p
 aving the route to a mechanistic understanding of biological function and 
 providing the first essential step towards the development of new drugs. B
 ecause of the costs and challenges associated with experimental techniques
 \, structural biologists often turn to computational methods.\n\nThis cour
 se will present docking-based computational methods and related bioinforma
 tics approaches\, aiming at predicting how proteins interact with other bi
 omolecules or ligands. Lectures will provide the theoretical background on
  state-of-the-art algorithms for sampling and scoring docking models\, des
 cribe the use of low- and high-resolution information\, and conservation- 
 and coevolution-based interface prediction methods. Further\, to broaden t
 he scope of the course beyond protein-protein interactions\, we will cover
  protein-peptide docking\, data-driven molecular simulations\, and other r
 elevant topics in the field\, including modeling of large assemblies and m
 embrane proteins. Roughly half of the course wil consist of practical sess
 ions where the students will run computations on interesting biological pr
 oblems. Finally\, to encourage interaction between all participants and st
 imulate discussions\, students will be prompted to present their own resea
 rch\, both in flash presentations and poster sessions\, and bring their ow
 n research problems to dedicated troubleshooting sessions.
LOCATION:Izmir Biomedicine and Genome Center\nDokuz Eylül University Healt
 h Campus\nMithatpasa St. 58/5 35340\nBalcova\, Izmir/TURKEY
SUMMARY:EMBO practical course on Integrative Modelling of Biomolecular Inte
 ractions
URL;VALUE=URI:http://meetings.embo.org/event/20-biomolecular-interactions
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