The draft ICH E9 addendum on estimands and sensitivity analysis was released back in July 2017 and (more than 1000) comments are back. All stakeholders are gaining the necessary experience and familiarity with estimands along with the associated challenges and methodologies. The language and thinking behind causal inference is well suited to this area.

The PSI Scientific Committee have put together this one day meeting to share and discuss new emerging topics around estimands and the ICH addendum.

The aims of the event are to:

Share the feedback from the public consultation on the draft ICH E9 addendum 
Explore the estimand concept within health technology assessments 
Describe how casual inference fits into the area of estimands 
Present case studies illustrating the implementation of the estimand framework and the use of causal inference methodology