Speaker: Alison Etheridge OBE FRS - University of Oxford

About the Event:

When Mendelian genetics was rediscovered at the beginning of the 20th Century, it was widely believed to be incompatible with Darwin's theory of natural selection. The mathematical sciences, in the hands of pioneers such as Fisher, Haldane and Wright, played a fundamental role in the reconciliation of the two theories, and the new field of theoretical population genetics was born. But fundamental questions remained (and remain) unresolved. The genetic composition of a population can be changed by natural selection, mutation, mating, and other genetic, ecological and evolutionary mechanisms. How do they interact with one another, and what was their relative importance in shaping the patterns that we see today? Whereas the pioneers of the field could only observe genetic variation indirectly, by looking at traits of individuals in a population, researchers today have direct access to DNA sequences, but making sense of this wealth of data presents a major scientific challenge and mathematical models play a decisive role. In this lecture we'll discuss how to distill our understanding into workable models and then explore the remarkable power of simple mathematical caricatures in interrogating modern genetic data.

Attendance is free and open to all, but pre-registration is required: